Isochronic Tones vs. Binaural Beats
What seems at first to be moot is actually a pretty big plus point. With binaural beats, headphones are mandatory as a different sound is played into each ear. You need one headphone to play the left sound, and another to play the right, otherwise your brain won't "process" the binaural beat.
With isochronic tones, there is just one tone (i.e. iso / isolated) so there is no need to use headphones to get the results. You can just kick back, press play and listen.
Why is this a good thing? Well, it's fine to use headphones if you're on a train or a plane, but when you're in bed (a great time to use them) it can be a real pain in the rear to have ear-plugs in. Headphones almost necessitate laying on your back in one position. I like to roll when in bed! ;)
It's good to be able to listen to isochronic tones at any time, without worrying about having to plug plastic into your ears. This is a nice mark in the "for" column, however I have found that the results without headphones aren't quite as pronounced, so it's only half a point extra for this differentiator.